Two case studies of the successful treatment of neurofeedback of clients with suicidal depression will be presented. The neurofeedback methods are based upon Dr. Angelo Boleas Quadrant Brain Model of treatment. One follow-up study of 20 clients with suicidal depression showed a 90% success rate still after 24 months of follow-upOne of the case studies will be of an individual whose depression was one of many symptoms part of their post concussion syndrome as a result of multiple head injuries.